Copper-catalyzed chemoselective cross-coupling reaction of thioamides and α-diazocarbonyl compounds: Synthesis of enaminones
نویسندگان
چکیده
منابع مشابه
Palladium-catalyzed insertion of α-diazocarbonyl compounds for the synthesis of cyclic amino esters.
Two different cyclic amino esters are synthesized by palladium-catalyzed cross-coupling reaction of diazoesters with N-substituted-2-iodoanilines. Aryldiazoacetates lead to cyclic α-amino esters with an α-quaternary carbon centre in the presence of CO. Additionally, arylvinyldiazoacetates afford cyclic α,β-unsaturated γ-amino esters.
متن کاملPalladium-catalyzed cross-coupling of alpha-diazocarbonyl compounds with arylboronic acids.
Suzuki-Miyaura reaction of aryl and vinyl halides or triflates with organoboron reagents has developed into one of the most important C-C bond-forming reactions.1,2 The mild and simple reaction conditions, the availability of various boronic acids that are normally nontoxic and stable, and easy workup and separation of the products are some of the factors that are responsible for the increasing...
متن کاملEnantioselective preparation and chemoselective cross-coupling of 1,1-diboron compounds.
The simplicity, efficiency and generality of the transition-metal-catalysed Suzuki-Miyaura cross-coupling reaction has led to its application in the preparation of a wide variety of organic compounds. Cross-coupling of alkylboron derivatives, however, remains a major challenge, in particular with regard to stereochemical control. Here, we describe the preparation and reaction of highly opticall...
متن کاملsynthesis of 3-aryl-2h-benzo[b]-1,4-oxazines in [omim]bf4 and reduction of organic compounds in methylimidazolium formate
در این پروژه ترکیبات 3-آریل-2h-بنزو[b]-4،1-اکسازین ها از مواد اولیه تجاری مشتقات دو آمینو فنول و ?-هالو کتون های آروماتیک در مایع یونی 1-اکتیل-3-متیل ایمیدازولیوم تترا فلورو بورات([omim]bf4) سنتز شده است. این واکنش توسط باز پتاسیم کربنات محلول از طریق o-آلکیلاسیون و سپس یک واکنش آمیداسیون درون مولکولی خود بخود در مدت زمان کوتاه انجام می شود. ترکیبات 4،1-بنزوکسازین به این روش با بهره خوب تا آلی ...
15 صفحه اولcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2017
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2017.01.004